SANZAF has 32 functional offices throughout the country including the SANZAF National Diary Office in the Cape. The  Diary Office was established as a dedicated National Office in 1996 to serve SANZAF regions throughout South Africa in respect of the development of its unique SANZAF Diary, SANZAF Desk Pad, SANZAF Wall Calendar and other auxiliary publications. This office co-ordinated the research, design and development of the SANZAF interactive website. (e-Mail address: diary@sanzaf.org.za). Just as each office is unique in its architecture and location, so too are its management, staff and volunteer personnel.

Located at 381 Lower Main Road, Salt River is SANZAF’s new Western Cape Head Office and Centre for educational assistance as of 01 November 2008. The Western Cape Head Office is supported by the Special Projects & Fund Raising Office at 1 Thornton Road cnr Klipfontein Road, Athlone (e-Mail address: specialprojects@sanzaf.org.za) and the Bridgetown Office at the Masjid, Cornflower Street. In addition it has 3 satellite offices situated in historically poverty-stricken areas of Delft, Mitchells Plain and Elsies River. The Boland, West Coast and Garden Route communities are serviced by SANZAF branches in Paarl, Wellington, Stellenbosch, Worcester, Malmesbury, Atlantis, Vredenburg, Mossel Bay, George and Knysna.

It was the first SANZAF office to be established in 1974. It has grown from a humble 3m office and until April 2008 it was located at 156 Queen Street in the building named “Dar-us-Salaam” or House of Peace together with the MYM and the Al Qalam Newspaper. The FARD Skills Training Centre was housed at the Al Ibrahim Towers at 85 Victoria Street. On May 2008 SANZAF offices as well as the FARD Skills Training Centre were incorporated into one service delivery unit as its new premises at 91 Beatrice Street named the Zakah House. This building was funded by the Islamic Development Bank (IDB) and the Muslim community of South Africa. The Durban Office caters for the needs of the Muslims in the greater Durban area stretching from Isipingo in the South to Verulam in the North to Pinetown towards the interior. Branch offices are in Tongaat and Pietermaritzburg. The Pietermaritzburg office: (e-Mail adrress: pmb@sanzaf.org.za), situated in 34 Simeon Road, Raisethorpe, caters for the basic needs of the recipients in the immediate vicinity and surrounds.

Located in Fordsburg's busy Mint Road is SANZAF's Gauteng Regional Head Office. It serves the greater Johannesburg area, including Lenasia, Soweto, Eldorado Park and surrounding areas. The office busies itself primarily with establishing contact and assisting local community organisations in carrying out welfare work. But among all of SANZAF's offices, it has taken the lead in establishing formal contact with the Department of Welfare and the Department of Health in the interest of our recipients. Five full-time staff manage the affairs of the office, and also supervise the Pretoria office. The Pretoria office is charged with the collection and distribution of Zakáh in areas in and around Marabastad, Mabopane, Attridgeville, Soshanguve and Garankua. An office has also been opened in Lenasia.

SANZAF's Kimberley office is situated at the Moghul Park Madressa complex. It acts as a co-ordinating office for relief and welfare work in the region, serving such interests as Da'wah, health and education. The Kimberley office is destined to play a greater role in the future considering the growing Muslim population. It will also facilitate the establishment of further offices in the Northern Cape, Free State and North West Province.